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Article

Functionally Active Toll‐Like Receptor 3 on Human Primary and Metastatic Cancer Cells

8 Apr 2009

Abstract excerpt

Toll-like receptor 3 (TLR3) is a member of Toll-like receptors who recognize structurally conserved molecules derived from pathogens and trigger the immune response. To clarify if TLR3, is expressed in certain tumour cell lines and whether it is functional and what is the response of these cell lines to different concentrations of poly I:C treatment, we have screened SW480, SW620, FaDu and Detroit 562 cell lines...

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PMID: 19522763
DOI: 10.1111/j.1365-3083.2009.02262.x

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