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Article

Identification of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis.

The Journal of biological chemistry - 14 Aug 2009

Thoendel Matthew, Horswill Alexander R

Abstract excerpt

Staphylococcus aureus regulates the production of extracellular virulence factors using the agr quorum-sensing system. This regulatory system responds to a secreted peptide thiolactone signal called an autoinducing peptide (AIP). The biosynthesis of AIP requires AgrD, the peptide precursor of AIP, and the integral membrane endopeptidase AgrB. In this study, we performed a molecular analysis of AgrD to identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19520867
DOI: 10.1074/jbc.M109.031757
PMCID: PMC2756194

Genes

AIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis.PMID 19520867Read ↗

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