Article
Establishment and biological analysis of the EC109/CDDP multidrug-resistant esophageal squamous cell carcinoma cell line.
Oncology reports - 1 Jul 2009
Wen Jing, Zheng Bin, Hu Yi, Zhang Xu, Yang Hong, Luo Kong-Jia, Zhang Xing, Li Yong-Feng, Fu Jian-Hua
Abstract excerpt
The aim of this study was to establish a stable, drug-resistant esophageal squamous cell carcinoma (ESCC) cell line. The human ESCC cell line EC109 was exposed to cisplatin (CDDP) by pulse treatment to select for the drug-resistant subline, EC109/CDDP cells. The MTT assay was used to test the drug resistance of EC109 and EC109/CDDP cells. In addition, cellular morphological changes were observed using microscopy...
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