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Article

ABCG2 gene amplification and expression in esophageal cancer cells with acquired adriamycin resistance.

Molecular medicine reports - 1 Apr 2014

Liu Liang, Zuo Lian Fu, Guo Jian Wen

Abstract excerpt

Resistance to chemotherapeutic agents is the main reason for treatment failure in patients with cancer. The primary mechanism of multidrug resistance (MDR) is the overexpression of drug efﬂux transporters, including ATP‑binding cassette transporter G2 (ABCG2). To the best of our knowledge, the MDR mechanisms of esophageal cancer have not been described. An adriamycin (ADM)-resistant subline, Eca109/ADM, was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24535197
DOI: 10.3892/mmr.2014.1949

Genes

ADM
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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