Article
The influence of renin-angiotensin system genotypes on the antiproteinuric response to high doses of olmesartan in non-diabetic proteinuric nephropathies.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - 13 Nov 2013
Goyache-Goñi Begoña, Aranda-Lara Pedro, Reyes-Engels Armando, Frutos-Sanz Miguel A, Hernández-Marrero Domingo
Abstract excerpt
OBJECTIVE: To assess the antiproteinuric response to multifactorial treatment based on high doses of angiotensin II receptor antagonists (ARBs) (olmesartan) in patients with non-diabetic proteinuric nephropathies, according to three renin-angiotensin system (RAS) polymorphisms: insertion/deletion of the angiotensin converting enzyme (ACE) gene, the angiotensinogen gene M235T and the angiotensin II type 1 receptor...
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