Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Renin-angiotensin-aldosterone system gene polymorphisms and antihypertensive response to irbesartan in Chinese hypertensives.

Methods and findings in experimental and clinical pharmacology - 1 May 2008

Liu H, Zhang S, Jiang S, Mao G, Hong X, Yu Y, Zhang Y, Tang G, Xing H, Xu X

Abstract excerpt

The aim of this study was to determine whether specific single nucleotide polymorphisms (SNPs) and their reconstructed haplotypes in renin-angiotensin-aldosterone system (RAAS) genes were associated with antihypertensive reduction to irbesartan treatment. Thousand one forty-two hypertensives were recruited and received 150 mg irbesartan daily for 4 weeks. Blood pressures (BPs) and blood samples, at postdose on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensinogen
Share to Antihypertensive Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Biphenyl Compounds

Share to Blood Pressure

Share to Hypertension

Share to Renin-Angiotensin System

Share to Tetrazoles

Source

Identifiers

PMID: 18773126
DOI: 10.1358/mf.2008.30.4.1186077

Genes

DBP
AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Renin-angiotensin-aldosterone system gene polymorphisms and antihypertensive response to irbesartan in Chinese hypertensives.PMID 18773126Read ↗

Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor.Semantic proximity Read ↗

Effect of renin-angiotensin-aldosterone system gene polymorphisms on blood pressure response to antihypertensive treatment.Semantic proximity Read ↗

Association between polymorphisms in the renin-angiotensin-aldosterone system genes and essential hypertension in the Han Chinese population.Semantic proximity Read ↗

Do genetic variants of the Renin-Angiotensin system predict blood pressure response to Renin-Angiotensin system-blocking drugs?: a systematic review of pharmacogenomics in the Renin-Angiotensin system.Semantic proximity Read ↗

Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial.Semantic proximity Read ↗

Haplotype-based association of the renin-angiotensin-aldosterone system genes polymorphisms with essential hypertension among Han Chinese: the Fangshan studySemantic proximity Read ↗

The RAAS system SNPs polymorphism is associated with essential hypertension risk in rural areas in northern China.Semantic proximity Read ↗

Gene polymorphism of angiotensin II type 1 and type 2 receptors.Semantic proximity Read ↗

Haplotype association and synergistic effect of human aldosterone synthase (CYP11B2) gene polymorphisms causing susceptibility to essential hypertension in Indian patients.Semantic proximity Read ↗

Genetic polymorphisms influencing antihypertensive drug responsesSemantic proximity Read ↗

Renin-angiotensin-aldosterone system gene polymorphisms and hypertension in Hong Kong Chinese.Semantic proximity Read ↗

Are genetic polymorphisms in the renin-angiotensin-aldosterone system associated with essential hypertension? Evidence from genome-wide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.