Article
Annotation of non-synonymous single polymorphisms in human liver proteome by mass spectrometry.
Protein and peptide letters - 1 Mar 2010
Chen Ming, Yang Bing, Ying Wantao, He Fuchu, Qian Xiaohong
Abstract excerpt
A novel strategy to annotate nsSNP-peptides in human liver proteome based on LC-ESI-MS/MS and peptide database search was proposed. Totally 115 nsSNP-peptides in human liver proteins were annotated using our method. Among them, 42 peptides were found to be amino acid mutation, 73 peptides were wild type, 5 peptides were interpreted with both mutation and wild type. The function of nsSNP-peptide was predicted...
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