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Article

The onset of diabetes in three out of four sisters: a Japanese family with type 1 diabetes. A case report.

Endocrine journal - 1 Jan 2009

Kishi Akio, Kawabata Yumiko, Ugi Satoshi, Iwai Tamaki, Tanaka Yuki, Yoshizaki Takeshi, Uzu Takashi, Nishio Yoshihiko, Ikegami Hiroshi, Kashiwagi Atsunori, Maegawa Hiroshi

Abstract excerpt

Type 1A diabetes is an autoimmune disease characterized by the destruction of insulin-producing beta-cells in the pancreas. The HLA-DR and -DQ genes are well established as being associated with increased risk for type 1 diabetes. Moreover, polymorphisms in CTLA4 have been reported to be associat...

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Identifiers

PMID: 19506323
DOI: 10.1507/endocrj.k09e-079

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19506323-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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