Article
Integrins contribute to initial morphological development and process outgrowth in rat adult hippocampal progenitor cells.
Journal of molecular neuroscience : MN - 1 Mar 2010
Harper Matthew M, Ye Eun-Ah, Blong Christopher C, Jacobson Mark L, Sakaguchi Donald S
Abstract excerpt
Adult rat hippocampal progenitor cells (AHPCs) are self-renewing, multipotent neural progenitor cells (NPCs) that can differentiate into neurons, oligodendrocytes, and astrocytes. AHPCs contact a variety of molecular cues within their surrounding microenvironment via integrins. We hypothesize that integrin receptors are important for NPCs. In this study, we have examined the distribution of integrins in...
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