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Article

Chimeric integrins expressed in retinal ganglion cells impair process outgrowth in vivo.

Molecular and cellular neurosciences - 1 Apr 1995

Lilienbaum A, Reszka A A, Horwitz A F, Holt C E

Abstract excerpt

Integrin function in retinal ganglion cell (RGC) development was examined in vivo by transfecting genes encoding various dominant forms of the chicken beta 1 integrin subunit into intact eye primordia of Xenopus embryos. RGCs expressing the chimeric chicken/Xenopus integrin receptors exhibited a marked reduction in process outgrowth with only 27% extending an axon and 41% bearing dendrites compared to control...

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Identifiers

PMID: 7551566
DOI: 10.1006/mcne.1995.1013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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