Article
Chimeric integrins expressed in retinal ganglion cells impair process outgrowth in vivo.
Molecular and cellular neurosciences - 1 Apr 1995
Lilienbaum A, Reszka A A, Horwitz A F, Holt C E
Abstract excerpt
Integrin function in retinal ganglion cell (RGC) development was examined in vivo by transfecting genes encoding various dominant forms of the chicken beta 1 integrin subunit into intact eye primordia of Xenopus embryos. RGCs expressing the chimeric chicken/Xenopus integrin receptors exhibited a...
Topics
- Animals
- Axons
- Base Sequence
- Cell Division
- Cell Movement
- Cell Size
- Chick Embryo
- Dendrites
- Gene Expression
- Immunohistochemistry
- Integrins
- Molecular Sequence Data
- Phenotype
