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Article

PDCD4 inhibits the malignant phenotype of ovarian cancer cells

7 May 2009

Abstract excerpt

Programmed cell death 4 (PDCD4) is a newly identified tumor suppressor that can inhibit activator protein (AP)-1 activation and protein translation. Our previous studies indicate that lost or reduced PDCD4 expression is associated with the progression of ovarian carcinoma. However, direct evidence that PDCD4 inhibits malignant phenotype of human cancer cells is limited. In the present study, we found that PDCD4...

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PMID: 19493270
DOI: 10.1111/j.1349-7006.2009.01210.x

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