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Article

Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses.

Cancer research - 15 Jun 2009

Strauss Robert, Sova Pavel, Liu Ying, Li Zong Yi, Tuve Sebastian, Pritchard David, Brinkkoetter Paul, Möller Thomas, Wildner Oliver, Pesonen Sari, Hemminki Akseli, Urban Nicole, Drescher Charles, Lieber André

Abstract excerpt

We studied the susceptibility of primary ovarian cancer cells to oncolytic adenoviruses. Using gene expression profiling of cancer cells either resistant or susceptible to viral oncolysis, we discovered that the epithelial phenotype of ovarian cancer represents a barrier to infection by commonly...

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Share to Adenoviridae
Share to Epithelial Cells
Share to Genetic Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, SCID

Share to Oncolytic Virotherapy

Share to Ovarian Neoplasms

Share to Receptors, Virus

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Source

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Identifiers

PMID: 19491256
DOI: 10.1158/0008-5472.CAN-09-0645
PMCID: PMC2738419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19491256-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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