Article
Reciprocal effects of STAT5 and STAT3 in breast cancer.
Molecular cancer research : MCR - 1 Jun 2009
Walker Sarah R, Nelson Erik A, Zou Lihua, Chaudhury Mousumi, Signoretti Sabina, Richardson Andrea, Frank David A
Abstract excerpt
Breast cancer is often associated with inappropriate activation of transcription factors involved in normal mammary development. Two related transcription factors, signal transducer and activator of transcription (STAT) 5 and STAT3, play important and distinct roles in mammary development and both can be activated in breast cancer. However, the relative contribution of these STATs to mammary tumorigenesis is...
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