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Article

Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells

1 May 2009

Abstract excerpt

Members of the tetraspanin superfamily of proteins are implicated in a variety of complex cell processes including cell fusion. However, the contribution of individual tetraspanins to these processes has proved difficult to define. Here we report the use of recombinant extracellular regions of tetraspanins to investigate the role of specific members of this family in the fusion of monocytes to form multinucleated...

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Identifiers

PMID: 19489128
DOI: 10.1111/j.1365-2567.2008.02945.x

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