Article
A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study.
The Journal of rheumatology - 1 Jul 2009
Dennison Elaine M, Syddall Holly E, Jameson Karen A, Sayer Avan Aihie, Gaunt Tom R, Rodriguez Santiago, Day Ian N M, Cooper Cyrus, Lips Mirjam A
Abstract excerpt
OBJECTIVE: We sought evidence of association of candidate single nucleotide polymorphisms (SNP) within the growth hormone-insulin-like growth factor 1 (IGF1) axis, largely selected on the basis of functional data available at the time of our study, with adult bone mass. METHODS: Four hundred ninety-eight men and 468 women aged 59-71 years were recruited. A lifestyle questionnaire was administered, and bone...
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