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Article

Molecular-dynamics simulations of ELIC-a prokaryotic homologue of the nicotinic acetylcholine receptor.

Biophysical journal - 3 Jun 2009

Cheng Xiaolin, Ivanov Ivaylo, Wang Hailong, Sine Steven M, McCammon J Andrew

Abstract excerpt

The ligand-gated ion channel from Erwinia chrysanthemi (ELIC) is a prokaryotic homolog of the eukaryotic nicotinic acetylcholine receptor (nAChR) that responds to the binding of neurotransmitter acetylcholine and mediates fast signal transmission. ELIC is similar to the nAChR in its primary sequence and overall subunit organization, but despite their structural similarity, it is not clear whether these two...

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Identifiers

PMID: 19486673
DOI: 10.1016/j.bpj.2009.03.018
PMCID: PMC2711484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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