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Gene expression profiling of advanced‐stage serous ovarian cancers distinguishes novel subclasses and implicates <i>ZEB2</i> in tumor progression and prognosis

4 May 2009

Abstract excerpt

To elucidate the mechanisms of rapid progression of serous ovarian cancer, gene expression profiles from 43 ovarian cancer tissues comprising eight early stage and 35 advanced stage tissues were carried out using oligonucleotide microarrays of 18,716 genes. By non-negative matrix factorization analysis using 178 genes, which were extracted as stage-specific genes, 35 advanced stage cases were classified into two...

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PMID: 19486012
DOI: 10.1111/j.1349-7006.2009.01204.x

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