Article
Expression of beta-catenin and its mechanism of delocalization in intestinal-type early gastric cancer based on mucin expression.
Histology and histopathology - 1 Jul 2009
Lee Soo Han, Kang Hyun Jeong, Shin Dong-Hun, Cho Duk-Yeon, Song Jin Mi, Lee Han Cheol, Kim Gwang Ha, Song Geun Am, Sol Mee Young, Kim Jee Yeon, Choi Kyung Un, Lee Chang Hun, Huh Gi Young, Park Do Youn
Abstract excerpt
The biological characteristics of intestinal-type early gastric cancers (ICs) differ based on mucin phenotypes. Beta-catenin delocalization is a predictive marker of aggressive biological behavior (submucosal invasion and lymph node metastasis) of ICs. The presumptive causative genetic alterations leading to delocalization of beta-catenin in ICs are still controversial, and there are only a few reports regarding...
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