Article
Overexpression of follistatin in trout stimulates increased muscling.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jul 2009
Medeiros Erika F, Phelps Michael P, Fuentes Fernando D, Bradley Terence M
Abstract excerpt
Deletion or inhibition of myostatin in mammals has been demonstrated to markedly increase muscle mass by hyperplasia, hypertrophy, or a combination of both. Despite a remarkably high degree of conservation with the mammalian protein, the function of myostatin remains unknown in fish, many species of which continue muscle growth throughout the lifecycle by hyperplasia. Transgenic rainbow trout (Oncorhynchus...
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