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Biphasic Modulation of Apoptotic Pathways in <i>Cryptosporidium parvum</i> -Infected Human Intestinal Epithelial Cells

16 Dec 2008

Abstract excerpt

The impact of Cryptosporidium parvum infection on host cell gene expression was investigated by microarray analysis with an in vitro model using human ileocecal HCT-8 adenocarcinoma cells. We found changes in 333 (2.6%) transcripts at at least two of the five (6, 12, 24, 48, and 72 h) postinfection time points. Fifty-one of the regulated genes were associated with apoptosis and were grouped into five clusters...

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PMID: 19075026
DOI: 10.1128/iai.00955-08

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