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Intestinal Epithelial Cell Apoptosis following<i>Cryptosporidium parvum</i>Infection

1 Mar 2000

Abstract excerpt

Cryptosporidium parvum induces moderate levels of apoptosis of cultured human intestinal epithelial cells, which are maximal at 24 h after infection. Apoptosis is further increased in C. parvum-infected cells by inhibition of NF-kappaB. C. parvum infection also attenuates epithelial apoptosis induced by strongly proapoptotic agents. The data suggest C. parvum has developed strategies to limit apoptosis in order...

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PMID: 10678994
DOI: 10.1128/iai.68.3.1710-1713.2000

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