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Article

Radiation sensitivity increases with proliferation‐associated telomere dysfunction in nontransformed human epithelial cells

16 May 2009

Abstract excerpt

Epidemiological studies have demonstrated age differences among human adults in susceptibility to radiation, with cancer cases attributable to radiation being more frequent for older individuals at time of exposure. In addition to the notion that susceptibility increases because of progressive decline in DNA monitoring and immunosurveillance, telomere function is now emerging as a new and important factor in...

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Share to DNA Repair Mechanisms
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PMID: 19473118
DOI: 10.1111/j.1474-9726.2009.00488.x

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