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Article

Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region.

15 Nov 1991

Abstract excerpt

The class II region of the human major histocompatibility complex (MHC) may encode several genes controlling the processing of endogenous antigen and the presentation of peptide epitopes by MHC class I molecules to cytotoxic T lymphocytes. A previously described peptide supply factor (PSF1) is a member of the multidrug-resistance family of transporters and may pump cytosolic peptides into the membrane-bound...

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Identifiers

PMID: 1946428
DOI: 10.1073/pnas.88.22.10094

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