Article
Genome shuffling: Progress and applications for phenotype improvement.
Biotechnology advances - 1 Jan 2000
Gong Jixian, Zheng Huijie, Wu Zhijun, Chen Tao, Zhao Xueming
Abstract excerpt
Although rational method and global technique have been successfully applied in strain improvement respectively, the demand for engineering complex phenotypes required combinatorial approach. The technology of genome shuffling has been presented as a novel whole genome engineering approach for the rapid improvement of cellular phenotypes. This approach using recursive protoplast fusion with multi-parental strains...
Topics
- Genome
- Phenotype
- Protoplasts
