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Article

Comparative analysis of the sequences and structures of HIV-1 and HIV-2 proteases.

Proteins - 1 Jan 1991

Gustchina A, Weber I T

Abstract excerpt

The different isolates available for HIV-1 and HIV-2 were compared for the region of the protease (PR) sequence, and the variations in amino acids were analyzed with respect to the crystal structure of HIV-1 PR with inhibitor. Based on the extensive homology (39 identical out of 99 residues), models were built of the HIV-2 PR complexed with two different aspartic protease inhibitors, acetylpepstatin and a renin...

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Identifiers

PMID: 1946342
DOI: 10.1002/prot.340100406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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