Article
The slow:fast substitution ratio reveals changing patterns of natural selection in gamma-proteobacterial genomes.
The ISME journal - 1 Oct 2009
Shapiro B Jesse, Alm Eric
Abstract excerpt
Different microbial species are thought to occupy distinct ecological niches, subjecting each species to unique selective constraints, which may leave a recognizable signal in their genomes. Thus, it may be possible to extract insight into the genetic basis of ecological differences among lineages by identifying unusual patterns of substitutions in orthologous gene or protein sequences. We used the ratio of...
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