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Article

The heterogeneous selection landscape of genome evolution in prokaryotes.

Proceedings of the National Academy of Sciences of the United States of America - 12 May 2026

Kogay Roman, Karamycheva Svetlana, Rochman Nash D, Wolf Yuri I, Koonin Eugene V

Abstract excerpt

Evolution of prokaryote genomes appears to be defined by the interplay of selection for genome streamlining, deletion bias, and selection for functional diversification. The previously observed overall positive correlation between the strength of selection, measured as the ratio of nonsynonymous to synonymous nucleotide substitutions (dN/dS), points to diversification as the primary factor of prokaryote genome...

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Archaea
Bacteria
Evolution, Molecular
Genome, Archaeal
Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prokaryotic Cells

Selection, Genetic

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PMID: 42085166
DOI: 10.1073/pnas.2605871123
PMCID: PMC13167734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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