Article
Haptoglobin polymorphism and diabetic nephropathy in Brazilian diabetic patients.
Annals of human biology - 1 Jan 2000
Wobeto Vânia P A, Garcia Priscila M D, Zaccariotto Tânia R, Sonati Maria de Fátima
Abstract excerpt
Diabetic nephropathy (DN) has an important impact on morbidity/mortality in diabetic patients. Genetic factors are probably involved in the development of this microvascular complication. Haptoglobin (Hp) is a genetically polymorphic glycoprotein that forms stable complexes with plasma-free hemoglobin (Hb) providing protection against heme-induced oxidative stress and kidney damage. The aim of the present study...
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