Article
Haptoglobin polymorphism and diabetic retinopathy in Brazilian patients.
Diabetes research and clinical practice - 1 Sept 2007
Wobeto Vânia P A, Rosim Endrigo T, Melo Mônica B, Calliari Luís Eduardo P, Sonati Maria de Fátima
Abstract excerpt
Haptoglobin (Hp) is an acute phase protein with antioxidant and immunomodulatory properties. Three main genotypes/phenotypes (Hp1-1, Hp2-1 and Hp2-2) show distinct efficiencies in these activities and have been associated with susceptibility and outcome in several diseases, including diabetes mellitus (DM). It has been suggested that Hp polymorphism may influence the development of retinopathy, an important...
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