Article
MMP-13 promoter polymorphisms in patients with chronic periodontitis: effects on GCF MMP-13 levels and outcome of periodontal therapy.
Journal of clinical periodontology - 1 Jun 2009
Pirhan Demet, Atilla Gül, Emingil Gülnur, Tervahartiala Taina, Sorsa Timo, Berdeli Afig
Abstract excerpt
AIM: The aims of this study were to investigate (a) the matrix metalloproteinase-13 (MMP-13) promoter polymorphisms in severe, generalized chronic periodontitis (CP), (b) the relationship of periodontal therapy outcome with these genotypes and (c) gingival crevicular fluid (GCF) MMP-13 level-MMP-13 genotype correlation. MATERIALS AND METHODS: Genomic DNA was obtained from peripheral blood of 102 patients with...
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