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Article

Genetic variations in the human gelatinase A (matrix metalloproteinase-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis.

Journal of periodontology - 1 Jul 2005

Holla Lydie Izakovicova, Fassmann Antonin, Vasku Anna, Goldbergova Monika, Beranek Michal, Znojil Vladimír, Vanek Jiri, Vacha Jiri

Abstract excerpt

BACKGROUND: Gelatinase A (matrix metalloproteinase-2 [MMP-2]) has been shown to play an important role in the pathogenesis of several disorders, including periodontal diseases. In this study, we test the hypothesis that variations in this gene influence the development and severity of chronic periodontitis. METHODS: Four promoter polymorphisms (-1575G/A, -1306C/T, -790T/G, and -735C/T) were analyzed by polymerase...

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Source

Identifiers

PMID: 16018746
DOI: 10.1902/jop.2005.76.7.1056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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