Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP1A2 genotype modifies the association between coffee intake and the risk of hypertension.

Journal of hypertension - 1 Aug 2009

Palatini Paolo, Ceolotto Giulio, Ragazzo Fabio, Dorigatti Francesca, Saladini Francesca, Papparella Italia, Mos Lucio, Zanata Giuseppe, Santonastaso Massimo

Abstract excerpt

OBJECTIVES: The longitudinal relationship between coffee use and hypertension is still controversial. Cytochrome P450 1A2 (CYP1A2) is the main responsible enzyme for the metabolism of caffeine. The aim of the present study was to investigate the effect of coffee intake on the risk of developing hypertension needing antihypertensive treatment in individuals stratified by CYP1A2 genotype. DESIGN: We assessed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Coffee

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A2

Share to Epinephrine

Share to Follow-Up Studies

Share to Hypertension

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19451835
DOI: 10.1097/HJH.0b013e32832ba850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP1A2 genotype modifies the association between coffee intake and the risk of hypertension.PMID 19451835Read ↗

Association of coffee consumption and CYP1A2 polymorphism with risk of impaired fasting glucose in hypertensive patients.Semantic proximity Read ↗

CYP1A2 Genetic Variation, Coffee Intake, and Kidney Dysfunction.Semantic proximity Read ↗

The importance of CYP1A2 genetic polymorphism in relation to coffee intake and high blood pressure in the Romanian populationSemantic proximity Read ↗

Association between hypertension and coffee drinking based on CYP1A2 rs762551 single nucleotide polymorphism in TaiwaneseSemantic proximity Read ↗

The influence of CYP1A2 genotype in the blood pressure response to caffeine ingestion is affected by physical activity status and caffeine consumption level.Semantic proximity Read ↗

CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking.Semantic proximity Read ↗

Coffee, CYP1A2 genotype, and risk of myocardial infarction.Semantic proximity Read ↗

Gender and ethnicity modify the association between the CYP1A2 rs762551 polymorphism and habitual coffee intake: evidence from a meta-analysis.Semantic proximity Read ↗

Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension.Semantic proximity Read ↗

Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank.Semantic proximity Read ↗

Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant.Semantic proximity Read ↗

Coffee Consumption and CYP1A2 Polymorphism Involvement in Type 2 Diabetes in a Romanian PopulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.