Decreased expression of T-cell-associated immune markers predicts poor prognosis in patients with follicular lymphoma.

doi:10.1111/cas.15224

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Article

Decreased expression of T-cell-associated immune markers predicts poor prognosis in patients with follicular lymphoma.

Cancer science - 1 Feb 2022

Rai Shinya, Inoue Hiroaki, Sakai Kazuko, Hanamoto Hitoshi, Matsuda Mitsuhiro, Maeda Yasuhiro, Haeno Takahiro, Watatani Yosaku, Kumode Takahiro, Serizawa Kentaro, Taniguchi Yasuhiro, Hirase Chikara, Espinoza J Luis, Morita Yasuyoshi, Tanaka Hirokazu, Ashida Takashi, Tatsumi Yoichi, Nishio Kazuto, Matsumura Itaru

Abstract excerpt

We previously examined the utility of rituximab-bendamustine (RB) in patients with follicular lymphoma (FL) exhibiting less than optimal responses to 2 cycles of the R-CHOP chemotherapy regimen. The aim of this study was to identify molecular biomarkers that can predict prognosis in RB-treated patients in the context of the prospective cohort. We first analyzed the mutational status of 410 genes in diagnostic...

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PMID: 34837284
DOI: 10.1111/cas.15224
PMCID: PMC8819350

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