Article
Urea transport mediated by aquaporin water channel proteins.
Sub-cellular biochemistry - 1 Jan 2014
Li Chunling, Wang Weidong
Abstract excerpt
Aquaporins (AQPs) are a family of membrane water channels that basically function as regulators of intracellular and intercellular water flow. To date, thirteen aquaporins have been characterized. They are distributed wildly in specific cell types in multiple organs and tissues. Each AQP channel consists of six membrane-spanning alpha-helices that have a central water-transporting pore. Four AQP monomers assemble...
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