Article
[Effects of chronic fluoxetine treatment on catalepsy and immune response in mice genetically predisposed to freezing reaction: the role of 5-HT1A and 5-HT2A receptors and tph2 and SERT genes].
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova - 1 Jan 2000
Tikhonova M A, Al'perina E L, Tolstikova T G, Bazovkina D V, Di V Iu, Idova G V, Kulikov A V, Popova N K
Abstract excerpt
ASC/Icg (Antidepressant Sensitive Catalepsy) mouse strain selected for high predisposition to pinch-induced catalepsy is characterized by depressive-like behavior and impaired immune response. Chronic treatment with SSRI fluoxetine attenuated catalepsy manifestation and normalized a decreased number of rosette-forming cells (RFC) in spleen in ASC mice. Chronic fluoxetine administration had no effect on catalepsy...
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