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Article

Dynamic up-regulation of prodynorphin transcription in temporal lobe epilepsy.

Hippocampus - 1 Nov 2009

Pirker Susanne, Gasser Elisabeth, Czech Thomas, Baumgartner Christoph, Schuh Elisabeth, Feucht Martha, Novak Klaus, Zimprich Fritz, Sperk Günther

Abstract excerpt

Dynorphin neuropeptides are believed to act as endogenous anticonvulsants, though direct evidence for such a role in humans is sparse. We now report pronounced increases of prodynorphin mRNA expression in the dentate gyrus of patients with temporal lobe epilepsy in comparison to controls. We dete...

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Identifiers

PMID: 19437412
DOI: 10.1002/hipo.20633
PMCID: PMC3073604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19437412-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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