Article
Common polymorphic variation in the genetically diverse African insulin gene and its association with size at birth.
Human genetics - 1 Sept 2009
Petry Clive J, Rayco-Solon Pura, Fulford Anthony J C, Stead John D H, Wingate Dianne L, Ong Ken K, Sirugo Giorgio, Prentice Andrew M, Dunger David B
Abstract excerpt
The insulin variable number of tandem repeats (INS VNTR) has been variably associated with size at birth in non-African populations. Small size at birth is a major determinant of neonatal mortality, so the INS VNTR may influence survival. We tested the hypothesis, therefore, that genetic variation around the INS VNTR in a rural Gambian population, who experience seasonal variation in nutrition and subsequently...
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