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Article

Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling.

Nature reviews. Genetics - 1 Jun 2009

Beckers Johannes, Wurst Wolfgang, de Angelis Martin Hrabé

Abstract excerpt

The mouse is the leading mammalian model organism for basic genetic research and for studying human diseases. Coordinated international projects are currently in progress to generate a comprehensive map of mouse gene functions - the first for any mammalian genome. There are still many challenges ahead to maximize the value of the mouse as a model, particularly for human disease. These involve generating mice that...

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PMID: 19434078
DOI: 10.1038/nrg2578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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