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Article

A distinct role for secreted fibroblast growth factor-binding proteins in development.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 2009

Gibby Krissa A, McDonnell Kevin, Schmidt Marcel O, Wellstein Anton

Abstract excerpt

FGFs modulate diverse biological processes including embryonic development. Secreted FGF-binding proteins (BPs) can release FGFs from their local extracellular matrix storage, chaperone them to their cognate receptors, and thus modulate FGF signaling. Here we describe 2 chicken BP homologs (chBP) that show distinct expression peaks at embryonic days E7.5 (chBP2) and E11.5 (chBP1), although their tissue...

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Identifiers

PMID: 19433791
DOI: 10.1073/pnas.0810952106
PMCID: PMC2689014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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