Article
Metabolic phenotyping of genetically modified mice: An NMR metabonomic approach.
Biochimie - 1 Aug 2009
Rull Anna, Vinaixa Maria, Angel Rodríguez Miguel, Beltrán Raúl, Brezmes Jesús, Cañellas Nicolau, Correig Xavier, Joven Jorge
Abstract excerpt
Monocyte chemoattractant protein-1 (MCP-1) plays a relevant role in macrophage migration but recent findings suggest an additional role in lipid and glucose metabolism. We report the use of (1)H NMR spectroscopy as a useful complementary method to assess the metabolic function of this gene in a comparative strategy. This metabonomic analysis was rapid, simple, quantitative and reproducible, and revealed a...
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