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Article

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.

PloS one - 27 Feb 2008

Fearnside Jane F, Dumas Marc-Emmanuel, Rothwell Alice R, Wilder Steven P, Cloarec Olivier, Toye Ayo, Blancher Christine, Holmes Elaine, Tatoud Roger, Barton Richard H, Scott James, Nicholson Jeremy K, Gauguier Dominique

Abstract excerpt

Insulin resistance plays a central role in type 2 diabetes and obesity, which develop as a consequence of genetic and environmental factors. Dietary changes including high fat diet (HFD) feeding promotes insulin resistance in rodent models which present useful systems for studying interactions between genetic background and environmental influences contributing to disease susceptibility and progression. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18301746
DOI: 10.1371/journal.pone.0001668
PMCID: PMC2244706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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