[Parkin and mitochondria].

Abstract excerpt

Parkinson disease (PD) is the most common neurodegenerative disease, and the majority of PD cases involve the sporadic from of PD. Although the etiology of the sporadic form is unknown, mitochondrial dysfunction and oxidative stress are considered to play a prominent role in its pathogenesis. The discovery of the genes that are linked to the rare familial form of PD has provided crucial insights into the...

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