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Article

Redundant mitochondrial targeting signals in yeast adenylate kinase.

The Journal of biological chemistry - 9 Aug 2002

Schricker Roland, Angermayr Michaela, Strobel Gertrud, Klinke Sigrid, Korber Dorothee, Bandlow Wolfhard

Abstract excerpt

Yeast adenylate kinase (Aky2p, Adk1p) occurs simultaneously in cytoplasm and mitochondrial intermembrane space. It has no cleavable mitochondrial targeting sequence, and the signal for mitochondrial import and submitochondrial sorting is largely unknown. The extreme N terminus of Aky2p is able to direct cytoplasmic passengers to mitochondria. However, an Aky2 mutant lacking this sequence is imported with about...

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Identifiers

PMID: 12045196
DOI: 10.1074/jbc.M201561200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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