Genetic comparison of human immunodeficiency virus (HIV-1) isolates by polymerase chain reaction.

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Article

Genetic comparison of human immunodeficiency virus (HIV-1) isolates by polymerase chain reaction.

Journal of acquired immune deficiency syndromes - 1 Jan 1991

McCutchan F E, Sanders-Buell E, Oster C W, Redfield R R, Hira S K, Perine P L, Ungar B L, Burke D S

Abstract excerpt

Amplification of DNA by polymerase chain reaction (PCR) is influenced by the homology of oligonucleotide primers with the DNA template. We have developed a procedure, termed anchored PCR, whereby nucleotide sequence alterations in the template can be directly related to the quantity of amplified...

Topics

Acquired Immunodeficiency Syndrome
Africa
Base Sequence
DNA, Viral
Genes, env
Genes, gag
Genes, nef
Genetic Variation
Genome, Viral
HIV-1
Humans
Molecular Sequence Data
North America
Oligonucleotide Probes
Polymerase Chain Reaction
Templates, Genetic

Source

Open in PubMed

Identifiers

PMID: 1941529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1941529-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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