Article
Kinase mutations and efficacy of imatinib in Korean patients with advanced gastrointestinal stromal tumors.
The oncologist - 1 May 2009
Kim Tae Won, Ryu Min-Hee, Lee Heungnam, Sym Sun Jin, Lee Jae-Lyun, Chang Heung Moon, Park Young Suk, Lee Kyung Hee, Kang Won Ki, Shin Dong Bok, Bang Yung-Jue, Lee Jung Shin, Kang Yoon-Koo
Abstract excerpt
PURPOSE: This study analyzed the relationship between treatment outcome and kinase mutational status in Korean patients with advanced gastrointestinal stromal tumors (GISTs). EXPERIMENTAL DESIGN: Clinical data were collected from 113 consecutive patients with metastatic or unresectable GISTs treated with imatinib from June 2001 through June 2005 at five institutions in Korea. KIT exons 9, 11, 13, and 17 and...
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