Article
Kinase mutations and imatinib mesylate response for 64 Taiwanese with advanced GIST: preliminary experience from Chang Gung Memorial Hospital.
Annals of surgical oncology - 1 Mar 2007
Yeh Chun-Nan, Chen Tsung-Wen, Lee Hsiang-Lin, Liu Yu-Yin, Chao Tzu-Chieh, Hwang Tsann-Long, Jan Yi-Yin, Chen Miin-Fu
Abstract excerpt
PURPOSE: Most gastrointestinal stromal tumors (GISTs) express constitutively activated mutation of kit or platelet-derived growth factor receptor alpha (PDGFRA), which are therapeutic targets for imatinib. Results of 64 Taiwanese with advanced GIST treated with imatinib were reported. METHOD AND MATERIALS: Between 2001 and May 2006, a prospective, non-randomized, and a single center trial containing 64 Taiwanese...
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