Article
A prospective, multicenter, phase 2 study of imatinib mesylate in korean patients with metastatic or unresectable gastrointestinal stromal tumor.
Oncology - 1 Jan 2009
Ryu Min-Hee, Kang Won Ki, Bang Yung-Jue, Lee Kyung Hee, Shin Dong Bok, Ryoo Baek-Yeol, Roh Jae Kyung, Kang Jin-Hyoung, Lee Hyoungnam, Kim Tae Won, Chang Heung Moon, Park Joon Oh, Park Young Suk, Kim Tae-You, Kim Min Kyoung, Lee Woon Kee, Kang Hye Jin, Kang Yoon-Koo
Abstract excerpt
OBJECTIVES: This prospective, multicenter, phase 2 study evaluated the efficacy and safety of imatinib mesylate and assessed KIT and PDGFRA gene mutation status in Korean patients with gastrointestinal stromal tumors (GISTs). METHODS: Forty-seven patients with pathologically proven KIT-positive metastatic or unresectable GISTs were accrued from eight institutions in Korea. Imatinib was administered orally at 400...
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