Article

Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins

2023-08-18

Abstract excerpt

<h4>ABSTRACT</h4> High levels of HDL-C are correlated with a decreased risk of cardiovascular disease. HDL-C levels are modulated in part by the secreted phospholipase, endothelial lipase (EL), which hydrolyzes the phospholipids of HDL and decreases circulating HDL-C concentrations. A 584C/T polymorphism in LIPG , the gene which encodes EL, was first identified in individuals with increased HDL levels. This poly...

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Literature Corpus work: 650cd348-a864-5ef1-a958-9bdddfc08c24
DOI: 10.1101/2023.08.18.553740

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