Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.

Cell - 1 May 2009

Kimura Yoko, Yashiroda Hideki, Kudo Tai, Koitabashi Sumiko, Murata Shigeo, Kakizuka Akira, Tanaka Keiji

Abstract excerpt

The dynamic and reversible process of ubiquitin modification controls various cellular activities. Ubiquitin exists as monomers, unanchored chains, or protein-conjugated forms, but the regulation of these interconversions remains largely unknown. Here, we identified a protein designated Rfu1 (regulator of free ubiquitin chains 1), which regulates intracellular concentrations of monomeric ubiquitins and free...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allosteric Regulation
Share to Endopeptidases
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomes

Share to Proteasome Endopeptidase Complex

Share to Ubiquitin

Share to Ubiquitin-Protein Ligase Complexes

Share to Ubiquitin Thiolesterase

Source

Identifiers

PMID: 19410548
DOI: 10.1016/j.cell.2009.02.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis.PMID 19410548Read ↗

Rfu1: stimulus for the ubiquitin economy.Semantic proximity Read ↗

The ubiquitin codes in cellular stress responsesSemantic proximity Read ↗

The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast.Semantic proximity Read ↗

The Ubiquitin–Proteasome System of <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

A ubiquitin stress response induces altered proteasome composition.Semantic proximity Read ↗

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism.Semantic proximity Read ↗

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.Semantic proximity Read ↗

Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase.Semantic proximity Read ↗

Dynamic transcription of ubiquitin genes under basal and stressful conditions and new insights into the multiple UBC transcript variantsSemantic proximity Read ↗

Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins.Semantic proximity Read ↗

Cdc48 cofactor Shp1 regulates signal-induced SCFMet30 disassembly.Semantic proximity Read ↗

A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.