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Article

Epigenome-Modifying Tools in Asthma

1 Sept 2015

Abstract excerpt

Asthma is a chronic disease which causes recurrent breathlessness affecting 300 million people worldwide of whom 250,000 die annually. The epigenome is a set of heritable modifications and tags that affect the genome without changing the intrinsic DNA sequence. These marks include DNA methylation, modifications to histone proteins around which DNA is wrapped and expression of noncoding RNA. Alterations in all of...

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PMID: 26479310
DOI: 10.2217/epi.15.53

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